Anti-SNRPD1 antibody (STJA0007440)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SNRPD1
General Information
| Short Description | Rabbit polyclonal anti-Small nuclear ribonucleoprotein Sm D1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNRPD1 |
| Gene ID | 6632 |
| Uniprot ID | SMD1_HUMAN |
| Immunogen | Synthesized peptide derived from human SNRPD1 |
| Specificity | This antibody detects endogenous levels of SNRPD1 at Human, Mouse |
Additional Info
| Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. |
| Protein Name | Small Nuclear Ribonucleoprotein Sm D1Sm-D1Sm-D AutoantigenSnrnp Core Protein D1 |
| Database Links | Reactome: R-HSA-191859Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-9754678 |
| Cellular Localisation | CytoplasmCytosolNucleusSmn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
| Alternative Antibody Names | Anti-Small Nuclear Ribonucleoprotein Sm D1 antibodyAnti-Sm-D1 antibodyAnti-Sm-D Autoantigen antibodyAnti-Snrnp Core Protein D1 antibodyAnti-SNRPD1 antibody |
Information sourced from Uniprot.org