| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SMYD1 (1-350) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SMYD1 |
| Gene ID: |
150572 |
| Uniprot ID: |
SMYD1_HUMAN |
| Immunogen Region: |
1-350 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1 (NP_938015.1). |
| Immunogen Sequence: |
MTIGRMENVEVFTAEGKGRG LKATKEFWAADIIFAERAYS AVVFDSLVNFVCHTCFKRQE KLHRCGQCKFAHYCDRTCQK DAWLNHKNECSAIKRYGKVP NENIRLAARIMWRVEREGTG LTEGCLVSVDDLQNHVEHFG EEEQKDLRVDVDTFLQYWPP QSQQFSMQYISHIFGVINCN GFTLSDQRGLQAVGVGIFPN LGLVNHDCWPNCTVIFNNGN HEAVKSMFHTQMRIELRAL |
| Tissue Specificity | Expression seems mostly restricted to heart and skeletal muscle. |
| Function | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
| Protein Name | Histone-Lysine N-Methyltransferase Smyd1Set And Mynd Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-9733709 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Smyd1 antibodyAnti-Set And Mynd Domain-Containing Protein 1 antibodyAnti-SMYD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
