Anti-SMARCAL1 antibody (485-535 aa) (STJ193690)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SMAL1 at the amino acid range 485-535
General Information
| Short Description | Rabbit polyclonal anti-SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (485-535 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reage |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMARCAL1 |
| Gene ID | 50485 |
| Uniprot ID | SMAL1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SMAL1 at the amino acid range 485-535 |
| Immunogen Region | 485-535 aa |
| Specificity | This antibody detects endogenous levels of SMAL1 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | DNA damage-regulated phosphorylation by kinases that may include ATM, ATR and PRKDC. |
| Function | ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. |
| Protein Name | Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1Hepa-Related ProteinHharpSucrose Nonfermenting Protein 2-Like 1 |
| Database Links | |
| Cellular Localisation | NucleusRecruited To Damaged Dna Regions |
| Alternative Antibody Names | Anti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1 antibodyAnti-Hepa-Related Protein antibodyAnti-Hharp antibodyAnti-Sucrose Nonfermenting Protein 2-Like 1 antibodyAnti-SMARCAL1 antibodyAnti-HARP antibody |
Information sourced from Uniprot.org