| Short Description : | Rabbit polyclonal anti-SRA stem-loop-interacting RNA-binding protein, mitochondrial for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLIRP |
| Gene ID: | 81892 |
| Uniprot ID: | SLIRP_HUMAN |
| Immunogen: | Synthesized peptide derived from human SLIRP |
| Specificity: | This antibody detects endogenous levels of SLIRP at Human, Mouse |
| Function | RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. |
| Protein Name | Sra Stem-Loop-Interacting Rna-Binding Protein - Mitochondrial |
| Database Links | Reactome: R-HSA-9836573 |
| Cellular Localisation | MitochondrionNucleusPredominantly MitochondrialSome Fraction Is NuclearIn The NucleusIt Is Recruited To Nuclear Receptor Target Promoters |
| Alternative Antibody Names | Anti-Sra Stem-Loop-Interacting Rna-Binding Protein - Mitochondrial antibodyAnti-SLIRP antibodyAnti-C14orf156 antibodyAnti-DC23 antibodyAnti-DC50 antibodyAnti-PD04872 antibody |
Information sourced from Uniprot.org
