| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC9A3R2 (180-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NHERF2 |
| Gene ID: |
9351 |
| Uniprot ID: |
NHRF2_HUMAN |
| Immunogen Region: |
180-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484). |
| Immunogen Sequence: |
DPGSPAARSGLRAQDRLIEV NGQNVEGLRHAEVVASIKAR EDEARLLVVDPETDEHFKRL RVTPTEEHVEGPLPSPVTNG TSPAQLNGGSACSSRSDLPG SDKDTEDGSAWKQDPFQESG L |
| Tissue Specificity | Widely expressed. |
| Function | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. |
| Protein Name | Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf2Nherf-2Nhe3 Kinase A Regulatory Protein E3karpSry-Interacting Protein 1Sip-1Sodium-Hydrogen Exchanger Regulatory Factor 2Solute Carrier Family 9 Isoform A3 Regulatory Factor 2Tyrosine Kinase Activator Protein 1Tka-1 |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinNucleusApical Cell MembraneLocalizes With Ezr And Podxl At The Apical Cell Membrane Of Glomerular Epithelium Cells And The Sides Of The Food ProcessesNuclearIn A Punctate Pattern |
| Alternative Antibody Names | Anti-Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf2 antibodyAnti-Nherf-2 antibodyAnti-Nhe3 Kinase A Regulatory Protein E3karp antibodyAnti-Sry-Interacting Protein 1 antibodyAnti-Sip-1 antibodyAnti-Sodium-Hydrogen Exchanger Regulatory Factor 2 antibodyAnti-Solute Carrier Family 9 Isoform A3 Regulatory Factor 2 antibodyAnti-Tyrosine Kinase Activator Protein 1 antibodyAnti-Tka-1 antibodyAnti-NHERF2 antibodyAnti-SLC9A3R2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
