Anti-SLC6A15 antibody (350-450) (STJ112468)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC6A15 (350-450) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC6A15 |
| Gene ID | 55117 |
| Uniprot ID | S6A15_HUMAN |
| Immunogen Region | 350-450 |
| Immunogen Sequence | LVVFAVLGFKANVINEKCIT QNSETIMKFLKMGNISQDII PHHINLSTVTAEDYHLVYDI IQKVKEEEFPALHLNSCKIE EELNKAVQGTGLAFIAFTEA M |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human SLC6A15 (NP_877499.1). |
Additional Info
| Tissue Specificity | Almost exclusively expressed in the brain. |
| Function | Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at2Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73Sodium-Coupled Branched-Chain Amino-Acid Transporter 1Solute Carrier Family 6 Member 15Transporter V7-3 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at2 antibodyAnti-Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 antibodyAnti-Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 15 antibodyAnti-Transporter V7-3 antibodyAnti-SLC6A15 antibodyAnti-B0AT2 antibodyAnti-NTT73 antibodyAnti-SBAT1 antibody |
Information sourced from Uniprot.org