Anti-SLC48A1 antibody (28-78 aa) (STJ196085)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HRG1 at the amino acid range 28-78
General Information
| Short Description | Rabbit polyclonal anti-Heme transporter HRG1 (28-78 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC48A1 |
| Gene ID | 55652 |
| Uniprot ID | HRG1_HUMAN |
| Immunogen | Synthesized peptide derived from the human HRG1 at the amino acid range 28-78 |
| Immunogen Region | 28-78 aa |
| Specificity | This antibody detects endogenous levels of HRG1 at Human/Mouse/Rat |
Additional Info
| Function | Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. In macrophages of the reticuloendothelial system, is the heme transporter for heme-iron recycling. Essential for macrophage iron homeostasis, transports heme from the phagolysosome to the cytoplasm during erythrophagocytosis (EP). |
| Protein Name | Heme Transporter Hrg1Heme-Responsive Gene 1 Protein HomologHrg-1Hhrg-1Solute Carrier Family 48 Member 1 |
| Database Links | |
| Cellular Localisation | Endosome MembraneMulti-Pass Membrane ProteinLysosome MembraneCytoplasmic VesiclePhagosome MembraneIn MacrophagesSpecifically Localizes To The Phagolysosomal Membranes During Erythrophagocytosis |
| Alternative Antibody Names | Anti-Heme Transporter Hrg1 antibodyAnti-Heme-Responsive Gene 1 Protein Homolog antibodyAnti-Hrg-1 antibodyAnti-Hhrg-1 antibodyAnti-Solute Carrier Family 48 Member 1 antibodyAnti-SLC48A1 antibodyAnti-HRG1 antibody |
Information sourced from Uniprot.org