| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-GLUT2 (1-100) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S3MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC2A2 |
| Gene ID: |
6514 |
| Uniprot ID: |
GTR2_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT2/SLC2A2 (P11168). |
| Immunogen Sequence: |
MTEDKVTGTLVFTVITAVLG SFQFGYDIGVINAPQQVIIS HYRHVLGVPLDDRKAINNYV INSTDELPTISYSMNPKPTP WAEEETVAAAQLITMLWSLS |
| Tissue Specificity | Liver, insulin-producing beta cell, small intestine and kidney. |
| Post Translational Modifications | N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells. |
| Function | Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2Glucose Transporter Type 2 - LiverGlut-2 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-210745Reactome: R-HSA-422356Reactome: R-HSA-5619098Reactome: R-HSA-8981373 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 antibodyAnti-Glucose Transporter Type 2 - Liver antibodyAnti-Glut-2 antibodyAnti-SLC2A2 antibodyAnti-GLUT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
