• Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GLUT-1 (PTR2138) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: HepG2Predicted band size: 54kDaObserved band size: 54kDa

Anti-SLC2A1 antibody (400-492) [PTR2138] (STJA0006245)

SKU:
STJA0006245

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Solute carrier family 2, facilitated glucose transporter member 1 (400-492) is suitable for use in Western Blot and ELISA research applications.
Clonality: Monoclonal
Clone ID: PTR2138
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC2A1
Gene ID: 6513
Uniprot ID: GTR1_HUMAN
Immunogen Region: 400-492
Specificity: This antibody detects endogenous levels of GLUT-1 at Human, Predict react with Mouse, Rat
Immunogen: Synthesized peptide derived from human GLUT-1 AA range: 400-492
Tissue Specificity Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Post Translational Modifications Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization.
Function Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1
Glucose Transporter Type 1 - Erythrocyte/Brain
Glut-1
Hepg2 Glucose Transporter
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-196836
Reactome: R-HSA-422356
Reactome: R-HSA-5619043
Reactome: R-HSA-5653890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Melanosome
Photoreceptor Inner Segment
Localizes Primarily At The Cell Surface
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibody
Anti-Glucose Transporter Type 1 - Erythrocyte/Brain antibody
Anti-Glut-1 antibody
Anti-Hepg2 Glucose Transporter antibody
Anti-SLC2A1 antibody
Anti-GLUT1 antibody

Information sourced from Uniprot.org

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