Anti-SLC26A8 antibody (82-132 aa) (STJ193744)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human S26A8 at the amino acid range 82-132
General Information
| Short Description | Rabbit polyclonal anti-Testis anion transporter 1 (82-132 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC26A8 |
| Gene ID | 116369 |
| Uniprot ID | S26A8_HUMAN |
| Immunogen | Synthesized peptide derived from the human S26A8 at the amino acid range 82-132 |
| Immunogen Region | 82-132 aa |
| Specificity | This antibody detects endogenous levels of S26A8 at Human/Mouse |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility. |
| Protein Name | Testis Anion Transporter 1Anion Exchange TransporterSolute Carrier Family 26 Member 8 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinLocated At Both The Annulus And The Equatorial Segment Of The Human Sperm Head |
| Alternative Antibody Names | Anti-Testis Anion Transporter 1 antibodyAnti-Anion Exchange Transporter antibodyAnti-Solute Carrier Family 26 Member 8 antibodyAnti-SLC26A8 antibodyAnti-TAT1 antibody |
Information sourced from Uniprot.org