Anti-SLC26A11 antibody (500-600) (STJ119420)

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STJ119420
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC26A11
Gene ID: 284129
Uniprot ID: S2611_HUMAN
Immunogen Region: 500-600
Specificity: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC26A11 (NP_001159819.1).
Immunogen Sequence: EILSRALEVSPPRCLVLECT HVCSIDYTVVLGLGELLQDF QKQGVALAFVGLQVPVLRVL LSADLKGFQYFSTLEEAEKH LRQEPGTQPYNIREDSILDQ K
Tissue Specificity Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart.
Function Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum.
Protein Name Sodium-Independent Sulfate Anion Transporter
Solute Carrier Family 26 Member 11
Database Links Reactome: R-HSA-427601
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lysosome Membrane
Apical Cell Membrane
Basolateral Cell Membrane
Alternative Antibody Names Anti-Sodium-Independent Sulfate Anion Transporter antibody
Anti-Solute Carrier Family 26 Member 11 antibody
Anti-SLC26A11 antibody

Information sourced from Uniprot.org