Tissue Specificity | Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart. |
Function | Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum. |
Protein Name | Sodium-Independent Sulfate Anion TransporterSolute Carrier Family 26 Member 11 |
Database Links | Reactome: R-HSA-427601 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLysosome MembraneApical Cell MembraneBasolateral Cell Membrane |
Alternative Antibody Names | Anti-Sodium-Independent Sulfate Anion Transporter antibodyAnti-Solute Carrier Family 26 Member 11 antibodyAnti-SLC26A11 antibody |
Information sourced from Uniprot.org