Anti-SLC25A24 antibody (162-212 aa) (STJ195121)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SCMC1 at the amino acid range 162-212
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial adenyl nucleotide antiporter SLC25A24-dependent solute carrier protein 1 (162-212 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A24 |
| Gene ID | 29957 |
| Uniprot ID | SCMC1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SCMC1 at the amino acid range 162-212 |
| Immunogen Region | 162-212 aa |
| Specificity | This antibody detects endogenous levels of SCMC1 at Human/Mouse |
Additional Info
| Function | Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a24Mitochondrial Atp-Mg/Pi Carrier Protein 1Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1Short Calcium-Binding Mitochondrial Carrier Protein 1Scamc-1Solute Carrier Family 25 Member 24 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a24 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 1 antibodyAnti-Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 1 antibodyAnti-Scamc-1 antibodyAnti-Solute Carrier Family 25 Member 24 antibodyAnti-SLC25A24 antibodyAnti-APC1 antibodyAnti-MCSC1 antibodyAnti-SCAMC1 antibody |
Information sourced from Uniprot.org