| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A23 (1-160) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A23 |
| Gene ID: |
79085 |
| Uniprot ID: |
SCMC3_HUMAN |
| Immunogen Region: |
1-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SLC25A23 (NP_077008.2). |
| Immunogen Sequence: |
MRGSPGDAERRQRWGRLFEE LDSNKDGRVDVHELRQGLAR LGGGNPDPGAQQGISSEGDA DPDGGLDLEEFSRYLQEREQ RLLLMFHSLDRNQDGHIDVS EIQQSFRALGISISLEQAEK ILHSMDRDGTMTIDWQEWRD HFLLHSLENVEDVLYFWKHS |
| Tissue Specificity | Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas. |
| Function | Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways. Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a23Mitochondrial Atp-Mg/Pi Carrier Protein 2Short Calcium-Binding Mitochondrial Carrier Protein 3Scamc-3Solute Carrier Family 25 Member 23 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a23 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 2 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 3 antibodyAnti-Scamc-3 antibodyAnti-Solute Carrier Family 25 Member 23 antibodyAnti-SLC25A23 antibodyAnti-APC2 antibodyAnti-MCSC2 antibodyAnti-SCAMC3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and SLC25A23 knockout (KO) 293T cells, using [KO Validated] SLC25A23 Rabbit polyclonal antibody (STJ11100753) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89691/358178/STJ11100753_1__66482.1713122487.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and SLC25A23 knockout (KO) 293T cells, using [KO Validated] SLC25A23 Rabbit polyclonal antibody (STJ11100753) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
