Anti-SLC25A21 antibody (134-183) (STJ94601)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial 2-oxodicarboxylate carrier (134-183) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A21 |
| Gene ID | 89874 |
| Uniprot ID | ODC_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183 |
| Immunogen Region | 134-183 |
| Specificity | ODC Polyclonal Antibody detects endogenous levels of ODC protein. |
Additional Info
| Tissue Specificity | Expressed in placenta, gall bladder and colon. |
| Function | Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle (Probable). |
| Protein Name | Mitochondrial 2-Oxodicarboxylate CarrierOdcMitochondrial 2-Oxoadipate CarrierSolute Carrier Family 25 Member 21 |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial 2-Oxodicarboxylate Carrier antibodyAnti-Odc antibodyAnti-Mitochondrial 2-Oxoadipate Carrier antibodyAnti-Solute Carrier Family 25 Member 21 antibodyAnti-SLC25A21 antibodyAnti-ODC antibody |
Information sourced from Uniprot.org