• Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100
  • Western blot analysis of extracts from K562, Jurkat cells, using BOCT Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-SLC22A17 antibody (Internal) (STJ96427)

SKU:
STJ96427

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Solute carrier family 22 member 17 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC22A17
Gene ID: 51310
Uniprot ID: S22AH_HUMAN
Immunogen Region: Internal
Specificity: BOCT Polyclonal Antibody detects endogenous levels of BOCT protein.
Immunogen: Synthesized peptide derived from the Internal region of human BOCT.
Function Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Protein Name Solute Carrier Family 22 Member 17
24p3 Receptor
24p3r
Brain-Type Organic Cation Transporter
Lipocalin-2 Receptor
Neutrophil Gelatinase-Associated Lipocalin Receptor
Ngalr
Database Links Reactome: R-HSA-917937
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Vacuole Membrane
Upon Lcn2-Binding
It Is Internalized
Alternative Antibody Names Anti-Solute Carrier Family 22 Member 17 antibody
Anti-24p3 Receptor antibody
Anti-24p3r antibody
Anti-Brain-Type Organic Cation Transporter antibody
Anti-Lipocalin-2 Receptor antibody
Anti-Neutrophil Gelatinase-Associated Lipocalin Receptor antibody
Anti-Ngalr antibody
Anti-SLC22A17 antibody
Anti-BOCT antibody
Anti-BOIT antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance