Anti-SLC1A6 antibody (320-370 aa) (STJ193578)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human Ethe amino acid4 at the amino acid range 320-370
General Information
| Short Description | Rabbit polyclonal anti-Excitatory amino acid transporter 4 (320-370 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC1A6 |
| Gene ID | 6511 |
| Uniprot ID | EAA4_HUMAN |
| Immunogen | Synthesized peptide derived from the human Ethe amino acid4 at the amino acid range 320-370 |
| Immunogen Region | 320-370 aa |
| Specificity | This antibody detects endogenous levels of EAA4 at Human/Mouse/Rat |
Additional Info
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). |
| Protein Name | Excitatory Amino Acid Transporter 4Sodium-Dependent Glutamate/Aspartate TransporterSolute Carrier Family 1 Member 6 |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 4 antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter antibodyAnti-Solute Carrier Family 1 Member 6 antibodyAnti-SLC1A6 antibodyAnti-EAAT4 antibody |
Information sourced from Uniprot.org