Anti-SLC1A2 antibody (370-420 aa) (STJ197400)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide derived from EAAT2 at the amino acid range 370-420
General Information
| Short Description | Rabbit polyclonal anti-Excitatory amino acid transporter 2 (370-420 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC1A2 |
| Gene ID | 6506 |
| Uniprot ID | EAA2_HUMAN |
| Immunogen | Synthetic peptide derived from EAAT2 at the amino acid range 370-420 |
| Immunogen Region | 370-420 aa |
| Specificity | EAAT2 protein (A223) detects endogenous levels of EAAT2 |
Additional Info
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. |
| Protein Name | Excitatory Amino Acid Transporter 2Glutamate/Aspartate Transporter IiSodium-Dependent Glutamate/Aspartate Transporter 2Solute Carrier Family 1 Member 2 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 2 antibodyAnti-Glutamate/Aspartate Transporter Ii antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter 2 antibodyAnti-Solute Carrier Family 1 Member 2 antibodyAnti-SLC1A2 antibodyAnti-EAAT2 antibodyAnti-GLT1 antibody |
Information sourced from Uniprot.org