| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC16A7 (379-478) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC16A7 |
| Gene ID: |
9194 |
| Uniprot ID: |
MOT2_HUMAN |
| Immunogen Region: |
379-478 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_001257551.1). |
| Immunogen Sequence: |
TIVECGPVLLGPPLAGKLVD LTGEYKYMYMSCGAIVVAAS VWLLIGNAINYRLLAKERKE ENARQKTRESEPLSKSKHSE DVNVKVSNAQSVTSERETNI |
| Tissue Specificity | Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells. |
| Function | Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate. |
| Protein Name | Monocarboxylate Transporter 2Mct 2Solute Carrier Family 16 Member 7 |
| Database Links | Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCytoplasmRequires The Ancillary ProteinEmb For Plasma Membrane LocalizationColocalizes With Bsg In SpermatozoaDetected In The Cytoplasm Of Sertoli Cells |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 2 antibodyAnti-Mct 2 antibodyAnti-Solute Carrier Family 16 Member 7 antibodyAnti-SLC16A7 antibodyAnti-MCT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
