| Tissue Specificity | Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells. |
| Function | Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate. |
| Protein Name | Monocarboxylate Transporter 2Mct 2Solute Carrier Family 16 Member 7 |
| Database Links | Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCytoplasmRequires The Ancillary ProteinEmb For Plasma Membrane LocalizationColocalizes With Bsg In SpermatozoaDetected In The Cytoplasm Of Sertoli Cells |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 2 antibodyAnti-Mct 2 antibodyAnti-Solute Carrier Family 16 Member 7 antibodyAnti-SLC16A7 antibodyAnti-MCT2 antibody |
Information sourced from Uniprot.org
