Anti-SLC16A7 antibody (379-478) (STJ25553)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC16A7 (379-478) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC16A7 |
| Gene ID | 9194 |
| Uniprot ID | MOT2_HUMAN |
| Immunogen Region | 379-478 |
| Immunogen Sequence | TIVECGPVLLGPPLAGKLVD LTGEYKYMYMSCGAIVVAAS VWLLIGNAINYRLLAKERKE ENARQKTRESEPLSKSKHSE DVNVKVSNAQSVTSERETNI |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_001257551.1). |
Additional Info
| Tissue Specificity | Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells. |
| Function | Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate. |
| Protein Name | Monocarboxylate Transporter 2Mct 2Solute Carrier Family 16 Member 7 |
| Database Links | Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneCytoplasmRequires The Ancillary ProteinEmb For Plasma Membrane LocalizationColocalizes With Bsg In SpermatozoaDetected In The Cytoplasm Of Sertoli Cells |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 2 antibodyAnti-Mct 2 antibodyAnti-Solute Carrier Family 16 Member 7 antibodyAnti-SLC16A7 antibodyAnti-MCT2 antibody |
Information sourced from Uniprot.org