Anti-SLC16A10 antibody (163-213 aa) (STJ195580)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MOT10 at the amino acid range 163-213
General Information
| Short Description | Rabbit polyclonal anti-Monocarboxylate transporter 10 (163-213 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC16A10 |
| Gene ID | 117247 |
| Uniprot ID | MOT10_HUMAN |
| Immunogen | Synthesized peptide derived from the human MOT10 at the amino acid range 163-213 |
| Immunogen Region | 163-213 aa |
| Specificity | This antibody detects endogenous levels of MOT10 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Not N-glycosylated. |
| Function | Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids. |
| Protein Name | Monocarboxylate Transporter 10Mct 10Aromatic Amino Acid Transporter 1Solute Carrier Family 16 Member 10T-Type Amino Acid Transporter 1 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 10 antibodyAnti-Mct 10 antibodyAnti-Aromatic Amino Acid Transporter 1 antibodyAnti-Solute Carrier Family 16 Member 10 antibodyAnti-T-Type Amino Acid Transporter 1 antibodyAnti-SLC16A10 antibodyAnti-MCT10 antibodyAnti-TAT1 antibody |
Information sourced from Uniprot.org