| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC16A10 (456-515) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC16A10 |
| Gene ID: |
117247 |
| Uniprot ID: |
MOT10_HUMAN |
| Immunogen Region: |
456-515 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 456-515 of human SLC16A10 (NP_061063.2). |
| Immunogen Sequence: |
GVPPLIGGAVLCFIPWIHSK KQREISKTTGKEKMEKMLEN QNSLLSSSSGMFKKESDSII |
| Tissue Specificity | Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart. |
| Post Translational Modifications | Not N-glycosylated. |
| Function | Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids. |
| Protein Name | Monocarboxylate Transporter 10Mct 10Aromatic Amino Acid Transporter 1Solute Carrier Family 16 Member 10T-Type Amino Acid Transporter 1 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 10 antibodyAnti-Mct 10 antibodyAnti-Aromatic Amino Acid Transporter 1 antibodyAnti-Solute Carrier Family 16 Member 10 antibodyAnti-T-Type Amino Acid Transporter 1 antibodyAnti-SLC16A10 antibodyAnti-MCT10 antibodyAnti-TAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
