| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC12A7 (1-70) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC12A7 |
| Gene ID: |
10723 |
| Uniprot ID: |
S12A7_HUMAN |
| Immunogen Region: |
1-70 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC12A7 (NP_006589.2). |
| Immunogen Sequence: |
MPTNFTVVPVEAHADGGGDE TAERTEAPGTPEGPEPERPS PGDGNPRENSPFLNNVEVEQ ESFFEGKNMA |
| Tissue Specificity | Detected in muscle, brain, lung, heart and kidney. |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. |
| Protein Name | Solute Carrier Family 12 Member 7Electroneutral Potassium-Chloride Cotransporter 4K-Cl Cotransporter 4 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 7 antibodyAnti-Electroneutral Potassium-Chloride Cotransporter 4 antibodyAnti-K-Cl Cotransporter 4 antibodyAnti-SLC12A7 antibodyAnti-KCC4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
