| Short Description : | Rabbit polyclonal SKIL (350-450) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SKIL |
| Gene ID: | 6498 |
| Uniprot ID: | SKIL_HUMAN |
| Immunogen Region: | 350-450 |
| Immunogen Sequence: | EMKEKFSMRSGKRNQSKTDA PSGMELQSWYPVIKQEGDHV SQTHSFLHPSYYLYMCDKVV APNVSLTSAVSQSKELTKTE ASKSISRQSEKAHSSGKLQK T |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SKIL (NP_005405.2). |
| Tissue Specificity | Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle. |
| Post Translational Modifications | Ubiquitinated by RNF111 and ARK2C, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling. |
| Function | May have regulatory role in cell division or differentiation in response to extracellular signals. |
| Protein Name | Ski-Like ProteinSki-Related OncogeneSki-Related Protein |
| Database Links | Reactome: R-HSA-2173795 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ski-Like Protein antibodyAnti-Ski-Related Oncogene antibodyAnti-Ski-Related Protein antibodyAnti-SKIL antibodyAnti-SNO antibody |
Information sourced from Uniprot.org
