| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Superkiller complex protein 3 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SKIC3 |
| Gene ID: |
9652 |
| Uniprot ID: |
SKI3_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TTC37 at Human |
| Immunogen: |
Synthesized peptide derived from human TTC37 |
| Function | Component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). |
| Protein Name | Superkiller Complex Protein 3Ski3Tetratricopeptide Repeat Protein 37Tpr Repeat Protein 37Tricho-Hepatic-Enteric Syndrome ProteinThespin |
| Database Links | Reactome: R-HSA-429958 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Superkiller Complex Protein 3 antibodyAnti-Ski3 antibodyAnti-Tetratricopeptide Repeat Protein 37 antibodyAnti-Tpr Repeat Protein 37 antibodyAnti-Tricho-Hepatic-Enteric Syndrome Protein antibodyAnti-Thespin antibodyAnti-SKIC3 antibodyAnti-KIAA0372 antibodyAnti-TTC37 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
