Anti-SKIC3 antibody (STJA0007703)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TTC37
General Information
| Short Description | Rabbit polyclonal anti-Superkiller complex protein 3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SKIC3 |
| Gene ID | 9652 |
| Uniprot ID | SKI3_HUMAN |
| Immunogen | Synthesized peptide derived from human TTC37 |
| Specificity | This antibody detects endogenous levels of TTC37 at Human |
Additional Info
| Function | Component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). |
| Protein Name | Superkiller Complex Protein 3Ski3Tetratricopeptide Repeat Protein 37Tpr Repeat Protein 37Tricho-Hepatic-Enteric Syndrome ProteinThespin |
| Database Links | Reactome: R-HSA-429958 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Superkiller Complex Protein 3 antibodyAnti-Ski3 antibodyAnti-Tetratricopeptide Repeat Protein 37 antibodyAnti-Tpr Repeat Protein 37 antibodyAnti-Tricho-Hepatic-Enteric Syndrome Protein antibodyAnti-Thespin antibodyAnti-SKIC3 antibodyAnti-KIAA0372 antibodyAnti-TTC37 antibody |
Information sourced from Uniprot.org