| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SHC-transforming protein 2 (261-310 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SHC2 |
| Gene ID: |
25759 |
| Uniprot ID: |
SHC2_HUMAN |
| Immunogen Region: |
261-310 aa |
| Specificity: |
Sck Polyclonal Antibody detects endogenous levels of Sck protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SHC2 at the amino acid range 261-310 |
| Post Translational Modifications | Phosphorylated on tyrosines by the Trk receptors. |
| Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. |
| Protein Name | Shc-Transforming Protein 2Protein SckShc-Transforming Protein BSrc Homology 2 Domain-Containing-Transforming Protein C2Sh2 Domain Protein C2 |
| Database Links | Reactome: R-HSA-167044Reactome: R-HSA-4420097Reactome: R-HSA-5673001 |
| Alternative Antibody Names | Anti-Shc-Transforming Protein 2 antibodyAnti-Protein Sck antibodyAnti-Shc-Transforming Protein B antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C2 antibodyAnti-Sh2 Domain Protein C2 antibodyAnti-SHC2 antibodyAnti-SCK antibodyAnti-SHCB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
