| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Endophilin-A1 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SH3GL2 |
| Gene ID: | 6456 |
| Uniprot ID: | SH3G2_HUMAN |
| Immunogen Region: | 30-110 aa |
| Specificity: | Endophilin I Polyclonal Antibody detects endogenous levels of Endophilin I protein. |
| Immunogen: | Synthesized peptide derived from Endophilin I at the amino acid range 30-110 |
| Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. |
| Protein Name | Endophilin-A1 Een-B1 Endophilin-1 Sh3 Domain Protein 2a Sh3 Domain-Containing Grb2-Like Protein 2 |
| Database Links | Reactome: R-HSA-177504 Reactome: R-HSA-182971 Reactome: R-HSA-2132295 Reactome: R-HSA-432720 Reactome: R-HSA-432722 Reactome: R-HSA-437239 Reactome: R-HSA-6807004 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8875360 |
| Cellular Localisation | Cytoplasm Membrane Peripheral Membrane Protein Early Endosome Presynapse |
| Alternative Antibody Names | Anti-Endophilin-A1 antibody Anti-Een-B1 antibody Anti-Endophilin-1 antibody Anti-Sh3 Domain Protein 2a antibody Anti-Sh3 Domain-Containing Grb2-Like Protein 2 antibody Anti-SH3GL2 antibody Anti-CNSA2 antibody Anti-SH3D2A antibody |
Information sourced from Uniprot.org