| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SH2D4A (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx. 55kDa band observed in Human Kidney lysates (calculated MW of 52.7kDa according to NP_071354.2). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SH2D4A |
| Gene ID: | 63898 |
| Uniprot ID: | SH24A_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_071354.2 |
| Immunogen Sequence: | HQKKESMKKKQDE |
| Function | Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. |
| Protein Name | Sh2 Domain-Containing Protein 4aProtein Sh(2aProtein Phosphatase 1 Regulatory Subunit 38 |
| Cellular Localisation | CytoplasmLocated At Podocyte Foot Processes |
| Alternative Antibody Names | Anti-Sh2 Domain-Containing Protein 4a antibodyAnti-Protein Sh(2a antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 38 antibodyAnti-SH2D4A antibodyAnti-PPP1R38 antibodyAnti-SH2A antibody |
Information sourced from Uniprot.org