| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SGIP1 (357-631) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SGIP1 |
| Gene ID: |
84251 |
| Uniprot ID: |
SGIP1_HUMAN |
| Immunogen Region: |
357-631 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 357-631 of human SGIP1 (NP_001295132.1). |
| Immunogen Sequence: |
MGAQDTLPVAAAFTETVNAY FKGADPSKCIVKITGEMVLS FPAGITRHFANNPSPAALTF RVINFSRLEHVLPNPQLLCC DNTQNDANTKEFWVNMPNLM THLKKVSEQKPQATYYNVDM LKYQVSAQGIQSTPLNLAVN WRCEPSSTDLRIDYKYNTDA MTTAVALNNVQFLVPIDGGV TKLQAVLPPAVWNAEQQRIL WKIPDISQKSENGGVGSLLA RFQLSEGPSKPSPLVVQFT |
| Tissue Specificity | Specifically expressed in brain. |
| Function | May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis. |
| Protein Name | Sh3-Containing Grb2-Like Protein 3-Interacting Protein 1Endophilin-3-Interacting Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | MembraneClathrin-Coated PitPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Sh3-Containing Grb2-Like Protein 3-Interacting Protein 1 antibodyAnti-Endophilin-3-Interacting Protein antibodyAnti-SGIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
