| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Splicing factor 3B subunit 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SF3B2 |
| Gene ID: |
10992 |
| Uniprot ID: |
SF3B2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SF3B2 at Human |
| Immunogen: |
Synthesized peptide derived from human SF3B2 |
| Function | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Splicing Factor 3b Subunit 2Pre-Mrna-Splicing Factor Sf3b 145 Kda SubunitSf3b145Spliceosome-Associated Protein 145Sap 145 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Splicing Factor 3b Subunit 2 antibodyAnti-Pre-Mrna-Splicing Factor Sf3b 145 Kda Subunit antibodyAnti-Sf3b145 antibodyAnti-Spliceosome-Associated Protein 145 antibodyAnti-Sap 145 antibodyAnti-SF3B2 antibodyAnti-SAP145 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
