Anti-SERPINC1 antibody (1-100) [S4MR] (STJ11101304)

Name: Anti-SERPINC1 antibody (1-100) [S4MR] (STJ11101304)
SKU: STJ11101304
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11101304

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Short Description	Rabbit monoclonal SERPINC1 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S4MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SERPINC1
Gene ID	462
Uniprot ID	ANT3_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MYSNVIGTVTSGKRKVYLLS LLLIGFWDCVTCHGSPVDIC TAKPRDIPMNPMCIYRSPEK KATEDEGSEQKIPEATNRRV WELSKANSRFATTFYQHLAD
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SERPINC1 (P01008).

Tissue Specificity	Found in plasma.
Post Translational Modifications	Phosphorylated by FAM20C in the extracellular medium.
Function	Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Protein Name	Antithrombin-Iii Atiii Serpin C1
Database Links	Reactome: R-HSA-140837 Reactome: R-HSA-140875 Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted Extracellular Space
Alternative Antibody Names	Anti-Antithrombin-Iii antibody Anti-Atiii antibody Anti-Serpin C1 antibody Anti-SERPINC1 antibody Anti-AT3 antibody Anti-PRO0309 antibody

Information sourced from Uniprot.org