| Host: |
Rabbit |
| Applications: |
WB/ICC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Septin 7 (286-435 aa) is suitable for use in Western Blot, Immunocytochemistry and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
R09-6A1 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: |
Affinity Purified |
| Concentration: |
0.3 mg/ml |
| Dilution Range: |
WB 1:500-1:1000IF 1:50-1:200 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: |
SEPTIN7 |
| Gene ID: |
989 |
| Uniprot ID: |
SEPT7_HUMAN |
| Immunogen Region: |
286-435 aa |
| Immunogen: |
Recombinant protein of human SEPT7 |
| Tissue Specificity | Widely expressed. |
| Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. |
| Protein Name | Septin-7Cdc10 Protein Homolog |
| Database Links | Reactome: R-HSA-5687128 |
| Cellular Localisation | CytoplasmChromosomeCentromereKinetochoreCytoskeletonSpindleCleavage FurrowMidbodyCilium AxonemeCell ProjectionCiliumFlagellumDistributed Throughout The Cytoplasm In Prometaphase CellsAssociated With The Spindle During MetaphaseAssociated With The Central Spindle And At The Cleavage Furrow In Anaphase CellsDetected At The Midbody In TelophaseAssociated With Actin Stress FibersFound In The Sperm Annulus |
| Alternative Antibody Names | Anti-Septin-7 antibodyAnti-Cdc10 Protein Homolog antibodyAnti-SEPTIN7 antibodyAnti-CDC10 antibodyAnti-SEPT7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
