• Western blot analysis of extracts of various cell lines, using Septin 11 antibody (STJ113941) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SEPT11 antibody (1-120) (STJ113941)

SKU:
STJ113941

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SEPT11 (1-120) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:2000-1:6000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SEPTIN11
Gene ID: 55752
Uniprot ID: SEP11_HUMAN
Immunogen Region: 1-120
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Septin 11 (NP_060713.1).
Immunogen Sequence: MAVAVGRPSNEELRNLSLSG HVGFDSLPDQLVNKSTSQGF CFNILCVGETGIGKSTLMDT LFNTKFESDPATHNEPGVRL KARSYELQESNVRLKLTIVD TVGFGDQINKDDSYKPIVEY
Tissue Specificity Widely expressed, except in leukocytes.
Function Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity. During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
Protein Name Septin-11
Cellular Localisation Cytoplasm
Cytoskeleton
Synapse
Cell Projection
Dendritic Spine
Axon
Partly Colocalizes With Stress Fibers And Microtubules
During Bacterial Infection
Displays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria
Alternative Antibody Names Anti-Septin-11 antibody
Anti-SEPTIN11 antibody
Anti-SEPT11 antibody

Information sourced from Uniprot.org

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