• Western blot analysis of lysates from SK-BR-3 cells, using SELE Rabbit polyclonal antibody (STJ25467) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-SELE antibody (22-230) (STJ25467)

SKU:
STJ25467

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SELE (22-230) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SELE
Gene ID: 6401
Uniprot ID: LYAM2_HUMAN
Immunogen Region: 22-230
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human SELE (NP_000441.2).
Immunogen Sequence: WSYNTSTEAMTYDEASAYCQ QRYTHLVAIQNKEEIEYLNS ILSYSPSYYWIGIRKVNNVW VWVGTQKPLTEEAKNWAPGE PNNRQKDEDCVEIYIKREKD VGMWNDERCSKKKLALCYTA ACTNTSCSGHGECVETINNY TCKCDPGFSGLKCEQIVNCT ALESPEHGSLVCSHPLGNFS YNSSCSISCDRGYLPSSMET MQCMSSGEW
Function Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Protein Name E-Selectin
Cd62 Antigen-Like Family Member E
Endothelial Leukocyte Adhesion Molecule 1
Elam-1
Leukocyte-Endothelial Cell Adhesion Molecule 2
Lecam2
Cd Antigen Cd62e
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-E-Selectin antibody
Anti-Cd62 Antigen-Like Family Member E antibody
Anti-Endothelial Leukocyte Adhesion Molecule 1 antibody
Anti-Elam-1 antibody
Anti-Leukocyte-Endothelial Cell Adhesion Molecule 2 antibody
Anti-Lecam2 antibody
Anti-Cd Antigen Cd62e antibody
Anti-SELE antibody
Anti-ELAM1 antibody

Information sourced from Uniprot.org

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