| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEC62 (258-399) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEC62 |
| Gene ID: |
7095 |
| Uniprot ID: |
SEC62_HUMAN |
| Immunogen Region: |
258-399 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 258-399 of human SEC62 (NP_003253.1). |
| Immunogen Sequence: |
GRHHFWFLPNLTADVGFIDS FRPLYTHEYKGPKADLKKDE KSETKKQQKSDSEEKSDSEK KEDEEGKVGPGNHGTEGSGG ERHSDTDSDRREDDRSQHSS GNGNDFEMITKEELEQQTDG DCEEDEEEENDGETPKSSHE KS |
| Function | Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. |
| Protein Name | Translocation Protein Sec62Translocation Protein 1Tp-1Htp-1 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Translocation Protein Sec62 antibodyAnti-Translocation Protein 1 antibodyAnti-Tp-1 antibodyAnti-Htp-1 antibodyAnti-SEC62 antibodyAnti-TLOC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
