| Short Description : | Rabbit polyclonal SEC62 (258-399) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEC62 |
| Gene ID: | 7095 |
| Uniprot ID: | SEC62_HUMAN |
| Immunogen Region: | 258-399 |
| Immunogen Sequence: | GRHHFWFLPNLTADVGFIDS FRPLYTHEYKGPKADLKKDE KSETKKQQKSDSEEKSDSEK KEDEEGKVGPGNHGTEGSGG ERHSDTDSDRREDDRSQHSS GNGNDFEMITKEELEQQTDG DCEEDEEEENDGETPKSSHE KS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-399 of human SEC62 (NP_003253.1). |
| Function | Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. |
| Protein Name | Translocation Protein Sec62Translocation Protein 1Tp-1Htp-1 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Translocation Protein Sec62 antibodyAnti-Translocation Protein 1 antibodyAnti-Tp-1 antibodyAnti-Htp-1 antibodyAnti-SEC62 antibodyAnti-TLOC1 antibody |
Information sourced from Uniprot.org
