| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Sec61A (350-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S0MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEC61A2 |
| Gene ID: |
55176 |
| Uniprot ID: |
S61A2_HUMAN |
| Immunogen Region: |
350-450 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Sec61A (Q9H9S3). |
| Immunogen Sequence: |
SMGAIFEDPVHVVVYIIFML GSCAFFSKTWIEVSGSSAKD VAKQLKEQQMVMRGHRDTSM VHELNRYIPTAAAFGGLCIG ALSVLADFLGAIGSGTGILL A |
| Function | Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. |
| Protein Name | Protein Transport Protein Sec61 Subunit Alpha Isoform 2Sec61 Alpha-2 |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-1799339 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec61 Subunit Alpha Isoform 2 antibodyAnti-Sec61 Alpha-2 antibodyAnti-SEC61A2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
