| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SDHAF2 (1-166) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SDHAF2 |
| Gene ID: |
54949 |
| Uniprot ID: |
SDHF2_HUMAN |
| Immunogen Region: |
1-166 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1). |
| Immunogen Sequence: |
MAVSTVFSTSSLMLALSRHS LLSPLLSVTSFRRFYRGDSP TDSQKDMIEIPLPPWQERTD ESIETKRARLLYESRKRGML ENCILLSLFAKEHLQHMTEK QLNLYDRLINEPSNDWDIYY WATEAKPAPEIFENEVMALL RDFAKNKNKEQRLRAPDLEY LFEKPR |
| Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. |
| Protein Name | Succinate Dehydrogenase Assembly Factor 2 - MitochondrialSdh Assembly Factor 2Sdhaf2 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Succinate Dehydrogenase Assembly Factor 2 - Mitochondrial antibodyAnti-Sdh Assembly Factor 2 antibodyAnti-Sdhaf2 antibodyAnti-SDHAF2 antibodyAnti-C11orf79 antibodyAnti-PGL2 antibodyAnti-SDH5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
