| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-SDCCAG8 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
SDCCAG8 |
| Gene ID: |
10806 |
| Uniprot ID: |
SDCG8_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_006633.1 |
| Immunogen Sequence: |
TINDQSQYIHHLEAE |
| Function | Plays a role in the establishment of cell polarity and epithelial lumen formation. Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis. |
| Protein Name | Serologically Defined Colon Cancer Antigen 8Antigen Ny-Co-8Centrosomal Colon Cancer Autoantigen ProteinHcccap |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCilium Basal BodyCell JunctionLocated At The Distal Ends Of Both Centrioles And Colocalizes To Centrosomes Throughout The Cell CycleIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Serologically Defined Colon Cancer Antigen 8 antibodyAnti-Antigen Ny-Co-8 antibodyAnti-Centrosomal Colon Cancer Autoantigen Protein antibodyAnti-Hcccap antibodyAnti-SDCCAG8 antibodyAnti-CCCAP antibodyAnti-NPHP10 antibodyAnti-HSPC085 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
