Anti-SDCCAG3 antibody (STJA0004649)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human SDCCAG3
General Information
| Short Description | Rabbit polyclonal anti-Endosome-Associated-Trafficking Regulator 1 for use in WB, IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ENTR1 |
| Gene ID | 10807 |
| Uniprot ID | ENTR1_HUMAN |
| Immunogen | Recombinant protein of human SDCCAG3 |
Additional Info
| Tissue Specificity | Expressed in the colon (at protein level). |
| Post Translational Modifications | Phosphorylated. |
| Function | Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis.the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis. |
| Protein Name | Endosome-Associated-Trafficking Regulator 1Antigen Ny-Co-3Serologically Defined Colon Cancer Antigen 3 |
| Database Links | |
| Cellular Localisation | CytoplasmEarly EndosomeEndosomeRecycling EndosomeMidbodyCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodyColocalizes In A Washc2-Dependent Manner With The Retromer Csc Complex At EndosomesDuring Cytokinesis Colocalized With Ptpn13 At The MidbodyColocalizes With Ift88 And Gamma-Tubulin At The Basal Body Of Primary CiliaColocalizes With Ift88 And Pericentrin At The Centrosome |
| Alternative Antibody Names | Anti-Endosome-Associated-Trafficking Regulator 1 antibodyAnti-Antigen Ny-Co-3 antibodyAnti-Serologically Defined Colon Cancer Antigen 3 antibodyAnti-ENTR1 antibodyAnti-SDCCAG3 antibody |
Information sourced from Uniprot.org