| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SCN3B (23-160) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:2000-1:8000IF/ICC 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SCN3B |
| Gene ID: |
55800 |
| Uniprot ID: |
SCN3B_HUMAN |
| Immunogen Region: |
23-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-160 of human SCN3B (NP_060870.1). |
| Immunogen Sequence: |
FPVCVEVPSETEAVQGNPMK LRCISCMKREEVEATTVVEW FYRPEGGKDFLIYEYRNGHQ EVESPFQGRLQWNGSKDLQD VSITVLNVTLNDSGLYTCNV SREFEFEAHRPFVKTTRLIP LRVTEEAGEDFTSVVSEI |
| Tissue Specificity | Expressed in the atrium. |
| Function | Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons. |
| Protein Name | Sodium Channel Subunit Beta-3 |
| Database Links | Reactome: R-HSA-445095Reactome: R-HSA-5576892 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sodium Channel Subunit Beta-3 antibodyAnti-SCN3B antibodyAnti-KIAA1158 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
