• Western blot analysis of lysate from mouse heart cells, using SCG3 Antibody.
  • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
  • Western blot analysis of mouse heart, mouse kidney cells using Sg III Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-SCG3 antibody (21-70 aa) (STJ96507)

SKU:
STJ96507

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Secretogranin-3 (21-70 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCG3
Gene ID: 29106
Uniprot ID: SCG3_HUMAN
Immunogen Region: 21-70 aa
Specificity: Sg III Polyclonal Antibody detects endogenous levels of Sg III protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3 at the amino acid range 21-70
Post Translational Modifications O-glycosylated.
Function Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Protein Name Secretogranin-3
Secretogranin Iii
Sgiii
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Secretory Vesicle Membrane
Peripheral Membrane Protein
Secreted
Associated With The Secretory Granule Membrane Through Direct Binding To Cholesterol-Enriched Lipid Rafts
Alternative Antibody Names Anti-Secretogranin-3 antibody
Anti-Secretogranin Iii antibody
Anti-Sgiii antibody
Anti-SCG3 antibody
Anti-UNQ2502 antibody
Anti-PRO5990 antibody

Information sourced from Uniprot.org

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