Anti-SCAI antibody [R05-3J2] (STJA0034841)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human SCAI
General Information
| Short Description | Rabbit monoclonal anti-SCAI for use in WB, IHC-F, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-3J2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SCAI |
| Gene ID | 286205 |
| Uniprot ID | SCAI_HUMAN |
| Immunogen | A synthetic peptide of human SCAI |
Additional Info
| Function | Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1. |
| Protein Name | Protein ScaiSuppressor Of Cancer Cell Invasion Protein |
| Database Links | Reactome: R-HSA-5663220 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinNucleusCytoplasmNuclear Localization Is Required For Inhibition Of Mrtfa |
| Alternative Antibody Names | Anti-Protein Scai antibodyAnti-Suppressor Of Cancer Cell Invasion Protein antibodyAnti-SCAI antibodyAnti-C9orf126 antibody |
Information sourced from Uniprot.org