| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SAM domain-containing protein SAMSN-1 (316-366 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SAMSN1 |
| Gene ID: |
64092 |
| Uniprot ID: |
SAMN1_HUMAN |
| Immunogen Region: |
316-366 aa |
| Specificity: |
This antibody detects endogenous levels of SAMN1 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human SAMN1 at the amino acid range 316-366 |
| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. |
| Protein Name | Sam Domain-Containing Protein Samsn-1Hematopoietic Adaptor Containing Sh3 And Sam Domains 1Nash1Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1Sh3-Sam Adaptor Protein |
| Cellular Localisation | NucleusCytoplasmCell ProjectionRuffleShuttles Between Cytoplasm And NucleusColocalizes With The Actin Cytoskeleton And Actin-Rich Membrane Ruffles |
| Alternative Antibody Names | Anti-Sam Domain-Containing Protein Samsn-1 antibodyAnti-Hematopoietic Adaptor Containing Sh3 And Sam Domains 1 antibodyAnti-Nash1 antibodyAnti-Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1 antibodyAnti-Sh3-Sam Adaptor Protein antibodyAnti-SAMSN1 antibodyAnti-HACS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
