Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-SAM domain-containing protein SAMSN-1 (316-366 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SAMSN1 |
Gene ID: | 64092 |
Uniprot ID: | SAMN1_HUMAN |
Immunogen Region: | 316-366 aa |
Specificity: | This antibody detects endogenous levels of SAMN1 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human SAMN1 at the amino acid range 316-366 |
Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. |
Protein Name | Sam Domain-Containing Protein Samsn-1Hematopoietic Adaptor Containing Sh3 And Sam Domains 1Nash1Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1Sh3-Sam Adaptor Protein |
Cellular Localisation | NucleusCytoplasmCell ProjectionRuffleShuttles Between Cytoplasm And NucleusColocalizes With The Actin Cytoskeleton And Actin-Rich Membrane Ruffles |
Alternative Antibody Names | Anti-Sam Domain-Containing Protein Samsn-1 antibodyAnti-Hematopoietic Adaptor Containing Sh3 And Sam Domains 1 antibodyAnti-Nash1 antibodyAnti-Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1 antibodyAnti-Sh3-Sam Adaptor Protein antibodyAnti-SAMSN1 antibodyAnti-HACS1 antibody |
Information sourced from Uniprot.org