| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SAFB2 |
| Gene ID: | 9667 |
| Uniprot ID: | SAFB2_HUMAN |
| Immunogen Region: | 1-255 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SAFB2 (NP_055464.1). |
| Immunogen Sequence: | MAETLPGSGDSGPGTASLGP GVAETGTRRLSELRVIDLRA ELKKRNLDTGGNKSVLMERL KKAVKEEGQDPDEIGIELEA TSKKSAKRCVKGLKMEEEGT EDNGLEDDSRDGQEDMEASL ENLQNMGMMDMSVLDETEVA NSSAPDFGEDGTDGLLDSFC DSKEYVAAQLRQLPAQPPEH AVDGEGFKNTLETSSLNFKV TPDIEESLLEPENEKILDIL GETCKSEPVKEESSELEQP |
| Tissue Specificity | Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines. |
| Function | Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. |
| Protein Name | Scaffold Attachment Factor B2Saf-B2 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Scaffold Attachment Factor B2 antibodyAnti-Saf-B2 antibodyAnti-SAFB2 antibodyAnti-KIAA0138 antibody |
Information sourced from Uniprot.org
