Anti-S1PR3 antibody (115-164 aa) (STJ92827)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human EDG3 at the amino acid range 115-164
General Information
| Short Description | Rabbit polyclonal anti-Sphingosine 1-phosphate receptor 3 (115-164 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | S1PR3 |
| Gene ID | 1903 |
| Uniprot ID | S1PR3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human EDG3 at the amino acid range 115-164 |
| Immunogen Region | 115-164 aa |
| Specificity | EDG-3 Polyclonal Antibody detects endogenous levels of EDG-3 protein. |
Additional Info
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
| Protein Name | Sphingosine 1-Phosphate Receptor 3S1p Receptor 3S1p3Endothelial Differentiation G-Protein Coupled Receptor 3Sphingosine 1-Phosphate Receptor Edg-3S1p Receptor Edg-3 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408Reactome: R-HSA-9009391 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibodyAnti-S1p Receptor 3 antibodyAnti-S1p3 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-3 antibodyAnti-S1p Receptor Edg-3 antibodyAnti-S1PR3 antibodyAnti-C9orf108 antibodyAnti-C9orf47 antibodyAnti-EDG3 antibody |
Information sourced from Uniprot.org