Host: | Rabbit |
Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-S100P (Full Length) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.65 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | S100P |
Gene ID: | 6286 |
Uniprot ID: | S100P_HUMAN |
Immunogen Region: | Full Length |
Immunogen: | Full length protein of human S100 beta/beta homodimer. |
Tissue Specificity | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
Function | May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). |
Protein Name | Protein S100-P Migration-Inducing Gene 9 Protein Mig9 Protein S100-E S100 Calcium-Binding Protein P |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | Nucleus Cytoplasm Cell Projection Microvillus Membrane Colocalizes With S100pbp In The Nucleus Colocolizes With Ezr In The Microvilli In A Calcium-Dependent Manner |
Alternative Antibody Names | Anti-Protein S100-P antibody Anti-Migration-Inducing Gene 9 Protein antibody Anti-Mig9 antibody Anti-Protein S100-E antibody Anti-S100 Calcium-Binding Protein P antibody Anti-S100P antibody Anti-S100E antibody |
Information sourced from Uniprot.org