| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | S100A11 |
| Gene ID: | 6282 |
| Uniprot ID: | S10AB_HUMAN |
| Immunogen Region: | 1-105 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1). |
| Immunogen Sequence: | MAKISSPTETERCIESLIAV FQKYAGKDGYNYTLSKTEFL SFMNTELAAFTKNQKDPGVL DRMMKKLDTNSDGQLDFSEF LNLIGGLAMACHDSFLKAVP SQKRT |
| Post Translational Modifications | Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation. |
| Function | Facilitates the differentiation and the cornification of keratinocytes. |
| Protein Name | Protein S100-A11CalgizzarinMetastatic Lymph Node Gene 70 ProteinMln 70Protein S100-CS100 Calcium-Binding Protein A11 Cleaved Into - Protein S100-A11 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Protein S100-A11 antibodyAnti-Calgizzarin antibodyAnti-Metastatic Lymph Node Gene 70 Protein antibodyAnti-Mln 70 antibodyAnti-Protein S100-C antibodyAnti-S100 Calcium-Binding Protein A11 Cleaved Into - Protein S100-A11 - N-Terminally Processed antibodyAnti-S100A11 antibodyAnti-MLN70 antibodyAnti-S100C antibody |
Information sourced from Uniprot.org