| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RXRG |
| Gene ID: | 6258 |
| Uniprot ID: | RXRG_HUMAN |
| Immunogen Region: | 1-137 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human RXRG (NP_008848.1). |
| Immunogen Sequence: | MYGNYSHFMKFPAGYGGSPG HTGSTSMSPSAALSTGKPMD SHPSYTDTPVSAPRTLSAVG TPLNALGSPYRVITSAMGPP SGALAAPPGINLVAPPSSQL NVVNSVSSSEDIKPLPGLPG IGNMNYPSTSPGSLVKH |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
| Post Translational Modifications | Acetylated by EP300. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. |
| Protein Name | Retinoic Acid Receptor Rxr-GammaNuclear Receptor Subfamily 2 Group B Member 3Retinoid X Receptor Gamma |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Gamma antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 3 antibodyAnti-Retinoid X Receptor Gamma antibodyAnti-RXRG antibodyAnti-NR2B3 antibody |
Information sourced from Uniprot.org
