Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RXRG (1-137) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RXRG |
Gene ID: |
6258 |
Uniprot ID: |
RXRG_HUMAN |
Immunogen Region: |
1-137 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human RXRG (NP_008848.1). |
Immunogen Sequence: |
MYGNYSHFMKFPAGYGGSPG HTGSTSMSPSAALSTGKPMD SHPSYTDTPVSAPRTLSAVG TPLNALGSPYRVITSAMGPP SGALAAPPGINLVAPPSSQL NVVNSVSSSEDIKPLPGLPG IGNMNYPSTSPGSLVKH |
Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
Post Translational Modifications | Acetylated by EP300. |
Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. |
Protein Name | Retinoic Acid Receptor Rxr-GammaNuclear Receptor Subfamily 2 Group B Member 3Retinoid X Receptor Gamma |
Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
Cellular Localisation | NucleusCytoplasm |
Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Gamma antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 3 antibodyAnti-Retinoid X Receptor Gamma antibodyAnti-RXRG antibodyAnti-NR2B3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance