Anti-RXRB antibody (283-298) (STJ11100090)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RXRB (283-298) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RXRB |
| Gene ID | 6257 |
| Uniprot ID | RXRB_HUMAN |
| Immunogen Region | 283-298 |
| Immunogen Sequence | AGKRLCAICGDRSSGKHYGV YSCEGCKGFFKRTIRKDLTY SCRDNKDCTVDKRQRNRCQY CRYQKCLATGMKREAVQEER QRGKDKDGDGEGAGGAPEEM PVDRILEAELAVEQKSDQGV EGPGGTGGSGSSPNDPVTNI CQAADKQLFTLVEWAKRIPH FSSLPLDDQVILLRAGWNEL LIASFSHRSIDVRDGILLAT GLHVHRNSAHSAGVGAIFDR VLTELVSKMRDMRMDKTEL |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human RXRB (NP_001257330.1). |
Additional Info
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). Expressed in monocytes. Expressed in a variety of tumor cell lines. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). |
| Protein Name | Retinoic Acid Receptor Rxr-BetaNuclear Receptor Subfamily 2 Group B Member 2Retinoid X Receptor Beta |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-9029558Reactome: R-HSA-9029569Reactome: R-HSA-9031525Reactome: R-HSA-9031528Reactome: R-HSA-9623433Reactome: R-HSA-9632974 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Beta antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 2 antibodyAnti-Retinoid X Receptor Beta antibodyAnti-RXRB antibodyAnti-NR2B2 antibody |
Information sourced from Uniprot.org